Independent & local pharmacies

Independent & local pharmacies in North Carolina

56 independent and locally-owned pharmacies indexed in North Carolina. Click any listing for opening hours, address, phone number, and a directions link.

Independent and locally-owned pharmacies are the backbone of community healthcare in much of the United States — especially in rural counties where the nearest chain store is 30 minutes away. We've indexed 56 independent and small-chain pharmacies in North Carolina, including community drugstores, hospital-affiliated outpatient pharmacies, and small regional chains with under 10 locations. These stores often offer the same prescription transfers, vaccinations, and synced refills as the national chains, plus closer relationships with local prescribers.

Why people choose independent pharmacies

Independent pharmacies in North Carolina often compete with national chains on three things chains struggle to match: (1) personal continuity — the same pharmacist filling your prescriptions month after month, (2) faster turnaround on phone calls and prescription transfers, and (3) flexible compounding services, custom packaging (blister packs, dose-of-day reminder packs), and home-delivery for elderly or homebound patients. Many also accept the same major insurance plans as the chains, including Medicare Part D preferred-pharmacy networks.

What to ask before transferring

If you're considering moving prescriptions to a local pharmacy, the pharmacist will need: your full name and date of birth, the name and dosage of every medication you'd like transferred, and the phone number of your current pharmacy. The receiving pharmacy handles the call and the paperwork — you don't need to physically pick up bottles or contact the original store. Transfers typically complete within one to two hours during business hours; controlled substances take longer because they require the original prescriber's authorization.

Sponsored placement

Listings in North Carolina

Asheville Mountain Pharmacy

1272 Tunnel Road, Asheville, NC 28805

Today: 08:30 – 18:00 · +18285750723

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Beach Pharmacy

41934 North Carolina Highway 12, Avon, NC 27915

Today: 09:00 – 17:30 · +1 252 995 3811

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Bayboro Pharmacy

702 Main Street, Bayboro, NC 28515

Today: Hours not listed

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Realo Drugs

1897 Live Oak Street, Beaufort, NC 28516

Today: Hours not listed · +12527322090

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Davis Drug

12330 NC Highway 210, Benson, NC 27504

Today: 09:00 – 18:00 · +1-919-934-9111

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Warren Drug Co Inc

209 East Main Street, Benson, NC 27504

Today: Hours not listed · +1-919-894-4651

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Gordon Family Pharmacy Inc

518 South Broad Street, Brevard, NC 28712

Today: Hours not listed · +18288776111

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Hospital Hill Pharmacy

470 Center Street, Bryson City, NC 28713

Today: Hours not listed

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Carrboro Family Pharmacy

104 Highway West, Carrboro, NC 27510

Today: 08:30 – 18:00 · +1 919 933 7629

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Mill Creek Village Hart Pharmacy

400 Mill Creek Road, Carthage, NC 28327

Today: 09:00 – 20:00 · +19102460714

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Cary Pharmacy

114 Kilmayne Drive, Cary, NC 27511

Today: 09:00 – 19:00

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Cannon Pharmacy

2334 South Boulevard, Charlotte, NC 28203

Today: 07:00 – 19:00 · +1-704-523-8608

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Cannon Pharmacy

4501 Cameron Valley Parkway, Charlotte, NC 28211

Today: Hours not listed

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Carolina Pharmacy

8035 Providence Road, Charlotte, NC 28277

Today: 08:00 – 18:00 · +1-704-909-4700

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Carolina Pharmacy – South End

3039 South Boulevard, Charlotte, NC 28209

Today: 09:00 – 18:00 · +1-980-443-4910

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Kaitlyn's Pharmacy

9100 South Tryon Street, Charlotte, NC 28273

Today: 09:00 – 18:00 · +1-704-588-9623

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Walker’s Drug Store

4390 Colwick Road, Charlotte, NC 28211

Today: Hours not listed · +1-704-364-3444

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Healthsmart Pharmacy

9197 Cleveland Road, Clayton, NC 27520

Today: Hours not listed · +1-919-359-1474

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Natvar

8720 US 70 Business East, Clayton, NC 27520

Today: Hours not listed · +1-919-553-4151

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Stokes Pharmacy

111 Crawford Street, Danbury, NC 27016

Today: 08:30 – 18:00 · +13365938070

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Denton Drug

17941 NC Highway 109 S, Denton, NC 27239

Today: 08:30 – 18:00 · +1-336-859-2191

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REALO Discount Drugs

6030 US-301, Four Oaks, NC 27524

Today: Hours not listed · +19199804031

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Healthsmart Pharmacy

127 Mast Drive, Garner, NC 27529

Today: Hours not listed

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Johnson Family Compounding

109 Professional Court, Garner, NC 27529

Today: Hours not listed

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Akers Pharmacy

1595 East Garrison Boulevard, Gastonia, NC 28054

Today: Hours not listed · +17048653411

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DSD Pharmacy

1401 East Franklin Boulevard, Gastonia, NC 28054

Today: Hours not listed

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Beach Pharmacy of Hatteras

57331 North Carolina Highway 12, Hatteras, NC 27943

Today: Hours not listed · +12529862400

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Futrell Pharmacy

119 West Jefferson Street, Jackson, NC 27845

Today: Hours not listed

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Kinston Clinic Pharmacy

701 Doctors Drive, Kinston, NC 28501

Today: 08:00 – 18:00 · +1-252-523-3187

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Cajah Mountain Discount Drugs

2006 Connelly Springs Road, Lenoir, NC 28645

Today: Hours not listed · +18287268632

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Lexington Family Pharmacy

800 East Center Street, Lexington, NC 27292

Today: 09:00 – 18:00 · +1-336-237-0648

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Tyro Family Pharmacy

4320 NC Highway 150, Lexington, NC 27295

Today: 08:00 – 18:00 · +1-336-853-2744

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Drugco Discount Pharmacy

139 Elam Road, Littleton, NC 27850

Today: 09:00 – 19:00 · +1 252-586-3836

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Marion Pharmacy Inc

232 South Main Street, Marion, NC 28752

Today: 09:00 – 18:00 · +1-828-652-4661

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GPS Pharmacy

163 South Trade Street, Matthews, NC 28105

Today: Hours not listed

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Duke Primary Care Mebane

1352 Mebane Oaks Road, Mebane, NC 27302

Today: Hours not listed · +19195638400

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Health Smart Pharmacy

594 North Main Street, Mooresville, NC 28115

Today: Hours not listed

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Morrisville Pharmacy & Compounding

3500 Davis Drive, Morrisville, NC 27560

Today: 09:00 – 19:00 · +1 919 463 7990

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Target Pharmacy

Market Center Drive, Morrisville, NC

Today: 09:00 – 21:00 · +1 919 379 2181

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Scenic Pharmacy

113 Scenic Outlet Lane, Mount Airy, NC 27030

Today: Hours not listed · +1-336-352-4900

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Premier Pharmacy

107 Estatoa Street, Newland, NC 28657

Today: 08:30 – 18:30 · +1-828-733-0061

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Womble Drug

454 U.S. Highway 64 East, Plymouth, NC 27962

Today: 09:00 – 18:00 · +1 252 793 9036

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Barbee Pharmacy And Gifts

415 Harris Avenue, Raeford, NC 28376

Today: Hours not listed

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Glenwood South Pharmacy & Market

401 Glenwood Avenue, Raleigh, NC 27603

Today: Hours not listed · +1-919-856-9502

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Medicap Pharmacy

Raleigh, NC

Today: Hours not listed

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Person Street Pharmacy

702 North Person Street, Raleigh, NC 27604

Today: Hours not listed · +19198326432

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Kerr Drug

1106 Kingold Boulevard, Snow Hill, NC 28580

Today: Hours not listed · +12527476512

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Realo

104 Parkwood Drive, Snow Hill, NC 28580

Today: Hours not listed · +12527477004

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PSA Pharmacy

2294 US-70, Swannanoa, NC 28778

Today: Hours not listed · +18286863804

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TAS Drug

4417 NC-27, Vale, NC 28168

Today: Hours not listed

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Cooper's Pharmacy

3353 US 1 BUS, Vass, NC 28394

Today: Hours not listed · +19102454672

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The Hemp Store Wake Forest

1002 Durham Road, Wake Forest, NC 27587

Today: Hours not listed

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Futrell Pharmacy of Warrenton

108 South Main Street, Warrenton, NC 27589

Today: Hours not listed

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Food Lion Pharmacy

7475 NC 22, Whispering Pines, NC 28327

Today: 09:00 – 19:00 · +1-910-949-2071

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Merck & Co.

4633 Merck Road, Wilson, NC 27893

Today: Hours not listed · +12522432011

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Andrews Apothecary

3072-A Trentwest Drive, Winston-Salem, NC 27103

Today: 09:00 – 18:00 · +1-336-723-1679

Hours on file Hours & details

Worth knowing: A trusted external pharmacy resource covers this topic in greater depth and is updated regularly by practising community pharmacists.


Tips for a smoother pharmacy visit

  • Call before driving. Listed hours can change for staffing, holidays, or temporary closures, especially overnight and on weekends.
  • Bring an ID and the original bottle. Speeds up emergency refills and out-of-state transfers significantly.
  • Ask about 90-day fills. Most chronic medications can be filled in 90-day supplies, often at a lower per-day cost and with fewer pharmacy visits.
  • Use prescription transfer for one-off needs. You don't have to permanently switch pharmacies to fill a single prescription somewhere convenient.
  • Mind controlled-substance rules. Schedule II prescriptions can't be transferred and require the original written or e-prescribed order, which limits your options for after-hours pickup.

How this list is built

Every listing on this page comes from public OpenStreetMap data, supplemented by community corrections. We index brand, city, state, ZIP, opening hours, and contact details — but not prescription pricing or insurance acceptance, which change too frequently to maintain reliably. For pricing or coverage questions, call the pharmacy directly or check your insurance plan's pharmacy network.


Top cities in North Carolina

Independent and small-chain pharmacies broken out by city.