Independent & local pharmacies in North Carolina
56 independent and locally-owned pharmacies indexed in North Carolina. Click any listing for opening hours, address, phone number, and a directions link.
Independent and locally-owned pharmacies are the backbone of community healthcare in much of the United States — especially in rural counties where the nearest chain store is 30 minutes away. We've indexed 56 independent and small-chain pharmacies in North Carolina, including community drugstores, hospital-affiliated outpatient pharmacies, and small regional chains with under 10 locations. These stores often offer the same prescription transfers, vaccinations, and synced refills as the national chains, plus closer relationships with local prescribers.
Why people choose independent pharmacies
Independent pharmacies in North Carolina often compete with national chains on three things chains struggle to match: (1) personal continuity — the same pharmacist filling your prescriptions month after month, (2) faster turnaround on phone calls and prescription transfers, and (3) flexible compounding services, custom packaging (blister packs, dose-of-day reminder packs), and home-delivery for elderly or homebound patients. Many also accept the same major insurance plans as the chains, including Medicare Part D preferred-pharmacy networks.
What to ask before transferring
If you're considering moving prescriptions to a local pharmacy, the pharmacist will need: your full name and date of birth, the name and dosage of every medication you'd like transferred, and the phone number of your current pharmacy. The receiving pharmacy handles the call and the paperwork — you don't need to physically pick up bottles or contact the original store. Transfers typically complete within one to two hours during business hours; controlled substances take longer because they require the original prescriber's authorization.
Listings in North Carolina
Asheville Mountain Pharmacy
1272 Tunnel Road, Asheville, NC 28805
Beach Pharmacy
41934 North Carolina Highway 12, Avon, NC 27915
Bayboro Pharmacy
702 Main Street, Bayboro, NC 28515
Realo Drugs
1897 Live Oak Street, Beaufort, NC 28516
Davis Drug
12330 NC Highway 210, Benson, NC 27504
Warren Drug Co Inc
209 East Main Street, Benson, NC 27504
Gordon Family Pharmacy Inc
518 South Broad Street, Brevard, NC 28712
Hospital Hill Pharmacy
470 Center Street, Bryson City, NC 28713
Carrboro Family Pharmacy
104 Highway West, Carrboro, NC 27510
Mill Creek Village Hart Pharmacy
400 Mill Creek Road, Carthage, NC 28327
Cary Pharmacy
114 Kilmayne Drive, Cary, NC 27511
Cannon Pharmacy
2334 South Boulevard, Charlotte, NC 28203
Cannon Pharmacy
4501 Cameron Valley Parkway, Charlotte, NC 28211
Carolina Pharmacy
8035 Providence Road, Charlotte, NC 28277
Carolina Pharmacy – South End
3039 South Boulevard, Charlotte, NC 28209
Kaitlyn's Pharmacy
9100 South Tryon Street, Charlotte, NC 28273
Walker’s Drug Store
4390 Colwick Road, Charlotte, NC 28211
Healthsmart Pharmacy
9197 Cleveland Road, Clayton, NC 27520
Natvar
8720 US 70 Business East, Clayton, NC 27520
Stokes Pharmacy
111 Crawford Street, Danbury, NC 27016
Denton Drug
17941 NC Highway 109 S, Denton, NC 27239
REALO Discount Drugs
6030 US-301, Four Oaks, NC 27524
Healthsmart Pharmacy
127 Mast Drive, Garner, NC 27529
Johnson Family Compounding
109 Professional Court, Garner, NC 27529
Akers Pharmacy
1595 East Garrison Boulevard, Gastonia, NC 28054
DSD Pharmacy
1401 East Franklin Boulevard, Gastonia, NC 28054
Beach Pharmacy of Hatteras
57331 North Carolina Highway 12, Hatteras, NC 27943
Futrell Pharmacy
119 West Jefferson Street, Jackson, NC 27845
Kinston Clinic Pharmacy
701 Doctors Drive, Kinston, NC 28501
Cajah Mountain Discount Drugs
2006 Connelly Springs Road, Lenoir, NC 28645
Lexington Family Pharmacy
800 East Center Street, Lexington, NC 27292
Tyro Family Pharmacy
4320 NC Highway 150, Lexington, NC 27295
Drugco Discount Pharmacy
139 Elam Road, Littleton, NC 27850
Marion Pharmacy Inc
232 South Main Street, Marion, NC 28752
GPS Pharmacy
163 South Trade Street, Matthews, NC 28105
Duke Primary Care Mebane
1352 Mebane Oaks Road, Mebane, NC 27302
Health Smart Pharmacy
594 North Main Street, Mooresville, NC 28115
Morrisville Pharmacy & Compounding
3500 Davis Drive, Morrisville, NC 27560
Target Pharmacy
Market Center Drive, Morrisville, NC
Scenic Pharmacy
113 Scenic Outlet Lane, Mount Airy, NC 27030
Premier Pharmacy
107 Estatoa Street, Newland, NC 28657
Womble Drug
454 U.S. Highway 64 East, Plymouth, NC 27962
Barbee Pharmacy And Gifts
415 Harris Avenue, Raeford, NC 28376
Glenwood South Pharmacy & Market
401 Glenwood Avenue, Raleigh, NC 27603
Medicap Pharmacy
Raleigh, NC
Person Street Pharmacy
702 North Person Street, Raleigh, NC 27604
Kerr Drug
1106 Kingold Boulevard, Snow Hill, NC 28580
Realo
104 Parkwood Drive, Snow Hill, NC 28580
PSA Pharmacy
2294 US-70, Swannanoa, NC 28778
TAS Drug
4417 NC-27, Vale, NC 28168
Cooper's Pharmacy
3353 US 1 BUS, Vass, NC 28394
The Hemp Store Wake Forest
1002 Durham Road, Wake Forest, NC 27587
Futrell Pharmacy of Warrenton
108 South Main Street, Warrenton, NC 27589
Food Lion Pharmacy
7475 NC 22, Whispering Pines, NC 28327
Merck & Co.
4633 Merck Road, Wilson, NC 27893
Andrews Apothecary
3072-A Trentwest Drive, Winston-Salem, NC 27103
Worth knowing: A trusted external pharmacy resource covers this topic in greater depth and is updated regularly by practising community pharmacists.
Tips for a smoother pharmacy visit
- Call before driving. Listed hours can change for staffing, holidays, or temporary closures, especially overnight and on weekends.
- Bring an ID and the original bottle. Speeds up emergency refills and out-of-state transfers significantly.
- Ask about 90-day fills. Most chronic medications can be filled in 90-day supplies, often at a lower per-day cost and with fewer pharmacy visits.
- Use prescription transfer for one-off needs. You don't have to permanently switch pharmacies to fill a single prescription somewhere convenient.
- Mind controlled-substance rules. Schedule II prescriptions can't be transferred and require the original written or e-prescribed order, which limits your options for after-hours pickup.
How this list is built
Every listing on this page comes from public OpenStreetMap data, supplemented by community corrections. We index brand, city, state, ZIP, opening hours, and contact details — but not prescription pricing or insurance acceptance, which change too frequently to maintain reliably. For pricing or coverage questions, call the pharmacy directly or check your insurance plan's pharmacy network.
Top cities in North Carolina
Independent and small-chain pharmacies broken out by city.