Pharmacy hours in North Carolina
178 pharmacy locations indexed across North Carolina. Use the lists below to jump to a city or brand, or scroll down for the full alphabetical store directory.
Top cities in North Carolina
Charlotte
North CarolinaRaleigh
North CarolinaWinston-Salem
North CarolinaMooresville
North CarolinaGreensboro
North CarolinaGastonia
North CarolinaGreenville
North CarolinaChapel Hill
North CarolinaKinston
North CarolinaGarner
North CarolinaNorth Wilkesboro
North CarolinaMorrisville
North CarolinaKernersville
North CarolinaLexington
North CarolinaMebane
North CarolinaWilson
North CarolinaHendersonville
North CarolinaLenoir
North CarolinaSnow Hill
North CarolinaWake Forest
North CarolinaHickory
North CarolinaCarrboro
North CarolinaHigh Point
North CarolinaThomasville
Brands operating in North Carolina
Walgreens
Independent Pharmacy
CVS Pharmacy
Rite Aid
Walmart Pharmacy
Target Pharmacy
Publix Pharmacy
The Medicine Shoppe
Sam's Club Pharmacy
Food Lion Pharmacy
All pharmacies in North Carolina
About pharmacies in North Carolina
North Carolina is regulated by its own state board of pharmacy, which sets the licensing rules, after-hours requirements, and continuing-education standards for pharmacists practising in the state. The opening hours of any individual pharmacy depend on a combination of brand policy, local demand, and staffing — chain stores in dense metropolitan areas often run 14 to 16 hours per day, with a smaller subset open 24 hours. Independent stores in smaller communities tend to mirror standard retail hours, typically 9am to 7pm on weekdays with shorter weekend windows.
If you're searching for after-hours coverage in North Carolina, your best bet is to start with the largest metro area in the list above and look for chain pharmacies attached to a 24-hour supermarket or big-box store. Hospital-connected pharmacies also frequently operate on extended schedules. For holiday closures — Thanksgiving, Christmas Day, Easter, and Independence Day — even chain stores often reduce hours, so always confirm by phone before making the trip.
Worth a read: A trusted external pharmacy resource covers this topic in greater depth and is updated regularly by practising community pharmacists.
Quick category finders for North Carolina
- 24-hour pharmacies in North Carolina
- Pharmacies open on Sunday in North Carolina
- After-hours / late-night pharmacies in North Carolina
- Independent & local pharmacies in North Carolina
What you'll find on each store page
Every store listed above links to its own page with the full street address, primary phone number, weekly hours table (Monday through Sunday), and any holiday notes we have collected. Where a pharmacy participates in immunization programs or operates a drive-through, the location page includes that detail. Hours can change without notice, so use the listed phone number to confirm before traveling.