After-hours & emergency pharmacies

After-hours & emergency pharmacies in Minnesota

14 late-night and emergency pharmacies indexed in Minnesota. Click any listing for opening hours, address, phone number, and a directions link.

Late-night prescription needs don't follow business hours. We've indexed 14 pharmacies in Minnesota that stay open until 9 pm or later (or operate around the clock), so you have a real option when your usual pharmacy has already closed for the day. Most stores on this list are large chain pharmacies inside grocery stores, drugstores, or mass-market retailers that maintain extended evening hours. Some 24-hour stores are also included; for true overnight coverage, see the dedicated 24-hour pharmacy finder.

What to do when your pharmacy is closed

If your usual pharmacy in Minnesota has closed for the day and you need a prescription urgently, you have three realistic options: (1) drive to a 24-hour or extended-hours store on the list below, (2) call your prescriber's after-hours line for a one-time emergency refill called into a different pharmacy, or (3) for chronic medications, ask any open pharmacist about a 72-hour emergency supply, which most state pharmacy boards allow without a fresh prescription if there is documented refill history.

Emergency prescription refills

Most US states have laws permitting a pharmacist to dispense an emergency supply of a maintenance medication (typically 72 hours, sometimes up to 30 days) when a refill cannot be obtained in time and the lapse would harm the patient. Insulin, blood-pressure, and heart medications are the most common scenarios. Call the open pharmacy first, explain the situation, and have the bottle from your previous fill ready so the pharmacist can verify the prescription history. If you can't reach a pharmacist, an urgent-care clinic or ER can also write a short-term bridge prescription.

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Listings in Minnesota

CVS Pharmacy

15051 Galaxie Avenue, Apple Valley, MN 55124

Today: 08:00 – 22:00

Hours on file Hours & details

Walgreens

5033 Vernon Avenue, Edina, MN 55436

Today: 08:00 – 22:00

Hours on file Hours & details

CVS Pharmacy

1175 Madison Avenue, Mankato, MN 56001

Today: Open 24 hours · +1-507-625-1791

Open now Hours & details

Cub Pharmacy

1800 Madison Avenue, Mankato, MN 56001

Today: 09:00 – 21:00

Hours on file Hours & details

Walgreens

13611 Grove Drive North, Maple Grove, MN 55311

Today: 09:00 – 21:00 · +17634207788

Hours on file Hours & details

CVS Pharmacy

1010 West Lake Street, Minneapolis, MN 55408

Today: Hours not listed

Hours on file Hours & details

CVS Pharmacy

818 Southeast Washington Avenue, Minneapolis, MN 55414

Today: 07:00 – 24:00

Hours on file Hours & details

Walgreens

630 Southeast Washington Avenue, Minneapolis, MN 55414

Today: 08:00 – 22:00

Hours on file Hours & details

Walgreens

1110 Larpenteur Avenue West, Roseville, MN 55113

Today: 08:00 – 22:00 · +1-651-488-5516

Hours on file Hours & details

CVS Pharmacy

4656 Excelsior Boulevard, Saint Louis Park, MN 55416

Today: 09:00 – 21:00 "Pharmacy"

Hours on file Hours & details

CVS Pharmacy

1040 Grand Avenue, Saint Paul, MN 55105

Today: 07:00 – 22:00 · +1-651-224-2155

Hours on file Hours & details

Cub Pharmacy

23800 Minnesota State Highway 7, Shorewood, MN 55331

Today: 09:00 – 21:00 · +1 952-380-9900

Hours on file Hours & details

Walmart Pharmacy

850 East County Road E, Vadnais Heights, MN 55127

Today: 07:00 – 23:00 · +1-651-486-7001

Hours on file Hours & details

Keaveny Drug, Winstead

150 Main Avenue West, Winsted, MN

Today: 8:30 – 6:00 · +1-320-485-2555

Hours on file Hours & details

Worth knowing: A trusted external pharmacy resource covers this topic in greater depth and is updated regularly by practising community pharmacists.


Tips for a smoother pharmacy visit

  • Call before driving. Listed hours can change for staffing, holidays, or temporary closures, especially overnight and on weekends.
  • Bring an ID and the original bottle. Speeds up emergency refills and out-of-state transfers significantly.
  • Ask about 90-day fills. Most chronic medications can be filled in 90-day supplies, often at a lower per-day cost and with fewer pharmacy visits.
  • Use prescription transfer for one-off needs. You don't have to permanently switch pharmacies to fill a single prescription somewhere convenient.
  • Mind controlled-substance rules. Schedule II prescriptions can't be transferred and require the original written or e-prescribed order, which limits your options for after-hours pickup.

How this list is built

Every listing on this page comes from public OpenStreetMap data, supplemented by community corrections. We index brand, city, state, ZIP, opening hours, and contact details — but not prescription pricing or insurance acceptance, which change too frequently to maintain reliably. For pricing or coverage questions, call the pharmacy directly or check your insurance plan's pharmacy network.