Pharmacies in Plano, Texas

21 pharmacies serving Plano and surrounding neighborhoods. Click any store for the full hours, address, and phone number.

Walgreens

Walgreens

6324 Custer Road
Hours on file · Hours not listed
Market Street

Market Street Pharmacy

1929 Preston Road
Hours on file · Hours not listed
Independent Pharmacy

Medscript Pharmacy

1101 Ohio Drive
Hours on file · Hours not listed
Independent Pharmacy

Southern Star Pharmacy

6101 Windhaven Parkway
Hours on file · 09:00 – 17:30
H-E-B Pharmacy

H-E-B Pharmacy

6001 Preston Road
Hours on file · 08:00 – 20:00
Tom Thumb

Tom Thumb Pharmacy

3945 Legacy Drive
Hours on file · Hours not listed
Kroger Pharmacy

Kroger Pharmacy

7100 Independence Parkway
Hours on file · Hours not listed
CVS Pharmacy

CVS Pharmacy

2101 West Spring Creek Parkway
Hours on file · Hours not listed
Independent Pharmacy

Tom Thumb Pharmacy

3100 Independence Parkway
Hours on file · Hours not listed
Kroger Pharmacy

Kroger Pharmacy

2925 Custer Road
Hours on file · Hours not listed
Walmart Pharmacy

Walmart Pharmacy

3100 Custer Road
Hours on file · Hours not listed
Walmart Pharmacy

Walmart Pharmacy

6000 Coit Road
Hours on file · Hours not listed
Walmart Pharmacy

Walmart Pharmacy

8040 Independence Parkway
Hours on file · Hours not listed
Walmart Pharmacy

Walmart Pharmacy

6001 North Central Expressway
Hours on file · Hours not listed
Kroger Pharmacy

Kroger Pharmacy

4017 14th Street
Hours on file · 09:00 – 20:00
Walmart Pharmacy

Walmart Pharmacy

3513 East Park Boulevard
Hours on file · 09:00 – 19:00
CVS Pharmacy

CVS Pharmacy

2200 Dallas Parkway
Hours on file · Hours not listed
Walmart Pharmacy

Walmart Pharmacy

3312 Preston Road
Hours on file · Hours not listed
Walgreens

Walgreens

Preston Road
Hours on file · 09:00 – 13:30, 14:00 – 20:00
Costco Pharmacy

Costco Pharmacy

1701 Dallas Parkway
Hours on file · 09:00 – 19:00
Costco Pharmacy

Costco Pharmacy

3800 Central Expressway
Hours on file · 09:00 – 19:00
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Pharmacy services in Plano

Plano, Texas is served by a mix of national chain pharmacies, supermarket-attached drug counters, and independent neighborhood stores. The list above covers every pharmacy we have on file in the Plano city limits, drawn from public mapping data and refreshed periodically. Most chain pharmacies in Plano operate from early morning through mid-evening, with a handful of 24-hour locations typically attached to flagship grocery or big-box stores.

If you need a same-day prescription transfer, call ahead — a pharmacist usually needs about 30 to 60 minutes to pull, verify, and label a transferred prescription, longer if your insurance information needs to be re-entered. For walk-in vaccinations (flu, COVID-19, shingles, Tdap, travel immunizations), most chains in Plano accept appointments through their corporate booking site, but same-day slots are usually available outside of peak flu season.

Holidays and after-hours

Even pharmacies that normally run extended hours often close earlier on Thanksgiving, Christmas Day, New Year's Day, and Easter Sunday. Independent pharmacies in Plano typically observe more federal holidays than the chains. The holiday hours guide has a full breakdown of what to expect by brand and by holiday, and we recommend always confirming with the store directly the day before a holiday visit.