Pharmacies in Plano, Texas

Pharmacy services in Plano

Plano, Texas is served by a mix of national chain pharmacies, supermarket-attached drug counters, and independent neighborhood stores. The list above covers every pharmacy we have on file in the Plano city limits, drawn from public mapping data and refreshed periodically. Most chain pharmacies in Plano operate from early morning through mid-evening, with a handful of 24-hour locations typically attached to flagship grocery or big-box stores.

If you need a same-day prescription transfer, call ahead — a pharmacist usually needs about 30 to 60 minutes to pull, verify, and label a transferred prescription, longer if your insurance information needs to be re-entered. For walk-in vaccinations (flu, COVID-19, shingles, Tdap, travel immunizations), most chains in Plano accept appointments through their corporate booking site, but same-day slots are usually available outside of peak flu season.

Holidays and after-hours

Even pharmacies that normally run extended hours often close earlier on Thanksgiving, Christmas Day, New Year's Day, and Easter Sunday. Independent pharmacies in Plano typically observe more federal holidays than the chains. The holiday hours guide has a full breakdown of what to expect by brand and by holiday, and we recommend always confirming with the store directly the day before a holiday visit.