CVS Pharmacy in South Carolina
16 CVS Pharmacy locations across 15 cities in South Carolina. Pick a city below for store-level hours and addresses.
Cities with CVS Pharmacy stores
Lexington
South CarolinaMyrtle Beach
South CarolinaGreenville
South CarolinaGreer
South CarolinaBatesburg-Leesville
South CarolinaMarion
South CarolinaColumbia
South CarolinaHonea Path
South CarolinaNewberry
South CarolinaJohns Island
South CarolinaSummerville
South CarolinaNorth Charleston
South CarolinaLadson
South CarolinaLiberty
South CarolinaNorth Myrtle Beach
All CVS Pharmacy locations in South Carolina
CVS Pharmacy in South Carolina: what to expect
CVS Pharmacy maintains 16 pharmacy locations across South Carolina, distributed across 15 distinct cities. The chain's footprint in this state mirrors its national pattern: dense clusters in the largest metropolitan areas, lighter coverage in suburban and rural counties, and occasional 24-hour flagship stores attached to high-traffic shopping centers.
Opening hours at CVS Pharmacy stores in South Carolina typically follow the brand's national template — extended weekday hours, slightly shorter Saturday schedules, and noticeably reduced Sunday windows — but specific stores vary based on local demand and labor availability. Stores located inside or attached to a 24-hour grocery operator usually offer the longest pharmacy windows. Standalone stores in residential neighborhoods often close by 9pm or earlier on weekdays.
Prescription transfers and refills
Moving an active prescription between two CVS Pharmacy locations in South Carolina is usually instant — the pharmacy systems share records — but transferring from another chain or an independent pharmacy requires a phone call from the receiving pharmacy to the original store. Allow at least an hour during normal business hours, longer at peak times. Refills can typically be scheduled through the chain's app or website, with text or email notifications when the prescription is ready.
Holiday hours
CVS Pharmacy stores in South Carolina generally observe the major federal holidays with reduced or zero hours. Thanksgiving and Christmas Day are the most likely full-closure days; New Year's Day, Easter, Memorial Day, Independence Day, and Labor Day usually run a shortened schedule. The store-level pages linked above include holiday notes wherever we have them, but always confirm by phone the day before.